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The Vaccine Education Center at Children’s Hospital of Philadelphia is excited to announce the release of our second animation showing how COVID-19 vaccines work. This one shows how viral vector vaccines, such as the J&J and AZ vaccines, work. Weakened adenoviruses can be used to deliver a vaccine. In COVID-19 vaccines, instructions to make the SARS-CoV-2 spike protein are delivered to educate the immune system, preparing it for future encounters with SARS-CoV-2. Learn more: http://COVIDVaccineAnswers.org
Thrombotic Thrombocytopenia Syndrome (TTS) has emerged as a new adverse event following immunization in individuals vaccinated with COVID-19 non-replicant adenovirus vector-based vaccines (AstraZeneca COVID-19 ChAdOx-1 vaccine and Johnson & Johnson (J&J) Janssen COVID-19 Ad26.COV2-S vaccine). TTS is a serious and life-threatening adverse event. WHO has issued this interim emergency guidance to increase awareness about TTS in the context of COVID-19 vaccination and help healthcare providers in the assessment and management of potential TTS cases. Knowledge about TTS following vaccination with a COVID-19 adenovirus vector-based vaccine is rapidly evolving. WHO will continue to monitor the situation closely for any changes that may affect this interim guidance and will update the guidance as needed.